An academic trial to study the prophylactic activity of Vishasura Kudineer(VSK)in healthcare workers exposed/non-exposed to COVID-19 patients.

Clinical evaluation for the prophylactic role of traditional Siddha formulation Vishasura Kudineer enlisted in Advisory of Ministry of AYUSH for COVID-19 - VSK

Status

Active, not recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/11/028905

Enrollment

120

Registered

2020-11-04

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: VSK decoction: 60 mL b.i.d for 1 month Intervention2: Vishasura Kudineer (VSK), a Siddha Formulation: The herbs used in VSK - 1.Azadirachta indica

2. Indigofera tinctorial

3. Zingiber officinale

4. Hemidesmus indicus

5. Aristolochia bracteolate

6. Vetiveria zizanioides

7. Glycyrrhiza glabra

8. Elettaria cardamomum

9. Santalum album Control Intervention1: Not Applicable: Not Applicable

Eligibility

Inclusion criteria

Inclusion criteria: Based on their personal and medical history; as well post clinical examination that includes biochemical, hematological and urinary parameters and also vital parameters such as - BP (100 â?? 139 mmHg systolic and 60â??89 mmHg diastolic); pulse rate in the range of 60â??100/min. Body temperature between 97.8 Ì? F and 99.0 Ì? F. Respiratory rate should be within the range of 14-18/min; will be included in this study. These volunteers should also be non-tobacco smoking or smokes requirements will be recruited.

Exclusion criteria

Exclusion criteria: History of any major surgical procedure in the past 3 months or with ailments such as diabetes mellitus, tuberculosis, dysphagia and systemic hypertension. History suggestive of cardiac, gastrointestinal, respiratory, hepatic, renal, endocrine, neurological, metabolic, psychiatric or hematological systems, judged to be clinically significant; and any other medical disorder that is of significance in the investigatorâ??s opinion

Design outcomes

Primary

Measure	Time frame
Chemical composition of VSK is expected to function as exogenous antioxidant and reduce the reactive oxygen species and enhance the endogenous antioxidants of the body; further it could prevent the cytokine storm and boost the immunity of the health care workers and thereby prevent the morbidity and mortality.Timepoint: one Month	—

Secondary

Measure	Time frame
The herbs in the VSK could reduce the stress and could elevate better psychological state in the health care workers.Timepoint: one month	—

Countries

India

Contacts

Public ContactDr R Shailaja

Narayana Medical College

livshiva@gmail.com8925744196

Outcome results