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Comparison of different types of fluid therapy in plastic reconstruction surgery

Impact of goal-directed versus liberal fluid therapy on flap outcome in micro vascular free flap reconstructive surgery : a randomised controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/11/028876
Enrollment
100
Registered
2020-11-04
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C140- Malignant neoplasm of pharynx, unspecified

Interventions

Intervention1: Goal directed fluid therapy: Restricting fluid administration to a patient undergoing micro vascular free flap surgery using goal directed fluid therapy methods Control Intervention1: N

Sponsors

Department of Anaesthesia
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Nyha class 1 - 3 Albumin > 2.5 gm/dl Weight 55 kg - 100 kg Operation duration > 120 min Blood loss > 1000 ml

Exclusion criteria

Exclusion criteria: Cognitive limitations Ejection fraction Patients with active cardiac dysrhythmia Pulmonary disease expected to prevent 8cc/kg tidal volumes Sleep apnea Renal disease

Design outcomes

Primary

MeasureTime frame
To compare the differences in intraoperative fluid administered for maintaining haemodynamic stability in case and control groupsTimepoint: Intraoperative and 48 hours—

Secondary

MeasureTime frame
To check the status of flap outcome post operatively for venous congestion,haematoma evacuation and reanaestomosisTimepoint: 48 hrs—

Countries

India

Contacts

Public ContactSarbari swaika

Government medical college

Dr.s.swaika@gmail.com8420405962

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026