PRF for bone regeneration in third molar socket

Evaluation of role of PRF in bone regeneration over exposed root surfaces of mandibular second molar after surgical removal of impacted third molar teeth

Status

Active, not recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/11/028865

Enrollment

100

Registered

2020-11-03

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Platelet Rich Fibrin: A single stage disimpaction of bilateral mandibular third molars will be performed under local anesthesia. Fresh autologous PRF will be placed on one side while th

Eligibility

Inclusion criteria

Inclusion criteria: Patients with bilateral impacted mandibular third molars leading to radiographic bone loss of >3 mm distal to second molar.

Exclusion criteria

Exclusion criteria: 1. Medically compromised and pregnant patients. 2. Patients with abnormal platelet counts ( 3. Patients with non-salvageable or missing second molars. 4. Patients with smoking and tobacco habit(s). 5. Patients with unacceptable oral hygiene (Plaque index >3) 1 week after oral prophylaxis. 6. Patients on medications which may interfere with wound healing.

Design outcomes

Primary

Measure	Time frame
Bone regeneration over exposed root surfaces of second mandibular molar teethTimepoint: 6 months	—

Secondary

Measure	Time frame
clinical attachment levelTimepoint: 3 months and 6 months;Pain, tendernees, Oedema and sensitivity at operated siteTimepoint: day 1 to month 3;Plaque index, sulcular bleeding index, Gingival indexTimepoint: week 1 to 6 months	—

Countries

India

Contacts

Public ContactDr Deborah Sybil

Jamia Millia Islamia

dsybilg@gmail.com09910766166

Outcome results