FindTrial
Sign In

Benefits of vitamin thiamine, vitamin C,vitamin B12 in children with severe infection - RCT

Randomised control study - To study effect of metabolic resuscitation with thiamine & vitamin C, B12 in pediatric severe sepsis

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/11/028825
Enrollment
200
Registered
2020-11-03
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B95-B97- Bacterial and viral infectious agents

Interventions

Intervention1: Injection Thiamine, Injection Vitamin C, Injection vitamin B12: Injection thiamine 100mg iv BD, injection Vitamin C 30mg/kg IV QID, injection vitamin B12 1000mcg IV od FOR 3 days Contro

Sponsors

Rainbow childrens hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All Cases of Severe sepsis and septic shock will be categorised to study grup and control group. Study group will receive inj Thiamine, vitamin C, Vitamin B12 along with standard treatment as per PICU protocol. Control group would receive only standard treatment as per PICU protocol

Exclusion criteria

Exclusion criteria: KNOWN CASE OF VITAMIN C,THIAMINE, B12 Deficiency cases of dilated cardiomyopathy INBORN ERROR OF METABOLISM RENAL STONES ALLERGY TO VITAMIN C, THIAMINE, B12

Design outcomes

Primary

MeasureTime frame
Mortality BenefitsTimepoint: Mortality Benefits—

Secondary

MeasureTime frame
Lactate levels, SOFA Scores VIS Scores, Length of PICU stay and hospital stayTimepoint: 5 Days—

Countries

India

Contacts

Public ContactDrLSuman

RAINBOW CHILDRENS HOSPITAL

paggy4u@gmail.com9592026143

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026