Comparison between chlorpromazine with olanzapine vs chlorpromazine alone in the treatment of hiccups in patients who had traumatic brain injury

Comparative evaluation of combination therapy with chlorpromazine and olanzapine vs chlorpromazine alone for treatment of hiccups in traumatic brain injury patients

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/11/028823

Enrollment

Registered

2020-11-03

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G998- Other specified disorders of nervous system in diseases classified elsewhere Health Condition 2: G998- Other specified disorders of nervous system in diseases classified elsewhere

Interventions

Intervention1: Comparitive evaluation of combination therapy with chlorpromazine and olanzapine vs chlorpromazine alone for the treatment of hiccups in traumatic brain injury patients: Patients with

Eligibility

Inclusion criteria

Inclusion criteria: Patients having intracranial injury confirmed by ct scan

Exclusion criteria

Exclusion criteria: Pregnant patients Patients with diabetes/copd/hypertension Patient with end organ damage Refusal to participate

Design outcomes

Primary

Measure	Time frame
Reduction in frequency of hiccups with combination vs monotherapyTimepoint: 4 weeks	—

Secondary

Measure	Time frame
Easy weaning from ventilator due to the remission of hiccupsTimepoint: 5 weeks	—

Countries

India

Contacts

Public ContactMeera Srinivasan

Institute of medical sciences, Banaras Hindu University

ghanshyambhu1976@gmail.com9838894169

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026