Health Condition 1: O742- Cardiac complications of anesthesia during labor and delivery
Conditions
Interventions
Intervention1: prophylactic dose of ondansetron, glycopyrrolate and ephedrine infusion: study group patients receive the following drugs
1. inj,glycopyrrolate 0.2mg IV once just before anaesthesia in
Sponsors
Vinayaka Missions Medical college
Eligibility
Inclusion criteria
Inclusion criteria: Healthy obstetric patients with no comorbidities posted for planned caesarean sections
Exclusion criteria
Exclusion criteria: parturients with significant systemic disorders Bleeding diathesis Emergency class 1 caesarean section Hypertensive disorders of pregnancy Fetal conditions precluding spinal anaesthesia Anticipated difficult spinal anaesthesia (spinal deformities, obesity, previous spine surgery etc)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean arterial pressure (mm Hg) Heart rate (beats per minute)Timepoint: Mean arterial pressure - baseline, before anaesthesia induction, and every 3 minutes thereafter till end of surgery. Heart rate - baseline, before induction of anaesthesia and every 3 minutes thereafter till end of surgery. | — |
Secondary
| Measure | Time frame |
|---|---|
| Total dose of ephedrine used Side effects - headache, vomiting, tachycardia, bradycardia, neonatal APGAR scoresTimepoint: Every 5 minutes after anaesthesia induction till 6 hour postoperatively At birth and at 3 and 5 minutes (APGAR score) | — |
Countries
India
Contacts
Public ContactIniya Rajendran
Vinayaka Missions Research foundation
Outcome results
None listed