Skip to content

Evaluation of clinical Disease status of Dental Pulp

Evaluation of Interleukin - 8 and TNF - alpha in Healthy and Inflamed Human Dental Pulp Tissue

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/11/028783
Enrollment
120
Registered
2020-11-02
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B998- Other infectious disease Health Condition 2: K040- Pulpitis

Interventions

Intervention1: Calcium silicate based cement placed over exposed pulp tissue: In teeth with reversible and symptomatic irreversible pulpitis,Caries will be removed by means of manual excavation and ro

Sponsors

MAULANA AZAD INSTITUTE OF DENTAL SCIENCES
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. normal pulp - no signs of pulpitis 2. reversible pulpitis - signs of reversible pulpitis as determined by clinical evaluation methods 3. irreversible pulpitis - signs of irreversible pulpal inflammation determined by patient evaluation, history and clinical tests

Exclusion criteria

Exclusion criteria: 1. Teeth with a negative response to cold test 2. Absence of apical radiolucency 3. Condensing apical periodontitis, 4. Internal/external root resorption, 5. History of trauma 6. Longitudinal root fracture or evidence of a periodontal-endodontic lesion on the day of treatment 7. Immunocompromised patients and those with systemic conditions 8. Periodontally compromised cases

Design outcomes

Primary

MeasureTime frame
Evaluation of inflammatory markers in collected blood samplesTimepoint: 6 months from enrolling the patient

Secondary

MeasureTime frame
long term maintenance of vitality of teeth treated with vitaal pulp therapy, corelation of ELISA results with clinical diagnosisTimepoint: 1 year and yearly thereafter

Countries

India

Contacts

Public ContactProf Dr Sangeeta Talwar

Maulana Azad Institute of Dental Sciences

sangeeta.talwar@gmail.com01123233925

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026