Health Condition 1: C250- Malignant neoplasm of head of pancreas
Conditions
Interventions
None listed
Sponsors
JIPMER intra mural research fund
Eligibility
Inclusion criteria
Inclusion criteria: All consecutive consenting patients aged more than 18 years who will be undergoing pancreatoduodenectomy with or without preoperative endoscopic biliary drainage for operable malignant tumors [Ampullary, periampullary, pancreatic and distal cholangiocarcinoma] causing distal biliary obstruction in the departments of surgery and surgical gastroenterology
Exclusion criteria
Exclusion criteria: a. Patients who had undergone percutaneous biliary drainage before pancreatoduodenectomy for operable malignant tumors [Ampullary, periampullary, pancreatic and distal cholangiocarcinoma] causing distal biliary obstruction b. Patients undergoing any additional procedure along with pancreatoduodenectomy, c. Patients who underwent preoperative endoscopic biliary drainage outside JIPMER
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the perioperative outcome (intraoperative and postoperative morbidity and mortality) between patients undergoing preoperative endoscopic biliary drainage and those undergoing upfront surgery without biliary drainage Timepoint: Intraoperative and upto 30th post operative day | — |
Secondary
| Measure | Time frame |
|---|---|
| To determine the frequency and indications of preoperative endoscopic biliary drainage among patients with malignant distal biliary obstruction undergoing pancreatoduodenectomy To compare the biliary microflora between patients undergoing preoperative endoscopic biliary drainage and those undergoing upfront surgery without biliary drainage Timepoint: Preoperative and Intra operative | — |
Countries
India
Contacts
Public ContactDr Siva Krishna Sirasapalli
Jawaharlal Institute of Post Graduate Medical Education and Research
Outcome results
None listed