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A study to compare between preoperative and postoperative misoprostol pushed rectally to control blood loss after cesarean section

Comparison between preoperative versus postoperative rectal misoprostol in controlling blood loss after cesarean section- a double blind randomized controlled trial.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/10/028736
Enrollment
126
Registered
2020-10-29
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O72- Postpartum hemorrhage

Interventions

Intervention1: Patients belonging to group 1 will be given rectal misoprostol before cesarean section: Patients belonging to group 1 will be given 2 tablets of misoprostol(each 200 microgram) per rec

Sponsors

IPGMER
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Pregnant women at term who are electively prepared for caesarean section under regional anaesthesia.

Exclusion criteria

Exclusion criteria: Antepartum haemorrhage, maternal hypertension, coagulation disorder, previous 2 or more caesarean section, multiple gestation, fetal macrosomia, polyhydramnios, previous uterine rupture, hypersensitivity to prostaglandin.

Design outcomes

Primary

MeasureTime frame
Blood loss within 2hours of birth: The suction bottle is changed following delivery of baby and blood loss is measured from the amount of blood collected in suction bottle plus weight of wet mops and drapings- weight of dry mops and drapings (assuming density 1gm /cc)plus blood loss every 15 minutes within 2hours after delivery from the weight of wet sanitary pads - weight of dry sanitary pads (assuming density 1gm /cc) Timepoint: 2 hours

Secondary

MeasureTime frame
1.Blood loss within 24hrs of birth at every moment the women discard sanitary pads (weight of wet sanitary pad minus weight of dry sanitary pad),2. Hemoglobulin and hematocrit before delivery and 24 hours after delivery, 3.Maternal death, maternal critical care unit admission, major surgical or invasive procedure, blood transfusion, adverse effects like vomiting, feverTimepoint: 24 hours

Countries

India

Contacts

Public ContactAnuradha Ghosh

IPGMER

khooshee@hotmail.com9830173132

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026