Health Condition 1: C718- Malignant neoplasm of overlappingsites of brain
Conditions
Interventions
Intervention1: induction agents IV ketofol or IV etomidate will be used: Patient with supratentorial craniotomy for elective craniotomy will be induced with either etomidate or ketofol and cerebral ox
Sponsors
AIIMS Rishikesh
Eligibility
Inclusion criteria
Inclusion criteria: 1. ASA I-II 2. Patients undergoing elective craniotomy for supratentorial tumour
Exclusion criteria
Exclusion criteria: 1.Patients with cerebrovascular disease (h/o stroke, carotid stenosis, aneurysm) 2.Patients with severe cardiovascular diseases (such as heart block, heart failure, left ventricular dysfunction) 3.Patients with Significant pulmonary, renal, hepatic or neuromuscular disease 4.Defined allergy to any of study drugs 5.Previous history of radiotherapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Cerebral oxygen saturation (NIRS)of both the affected and non-affected side 2.mean flow velocity of the middle cerebral artery of both the affected and non-affected side and its derivatives pulsality index and resistive index. Timepoint: 1.Baseline(immediately after arrival to operation theatre, T0) 2.Immediately after induction of anaesthesia(1 min) (T1) 3.Thereafter at 3, 5, 10 and 30 minutes post induction (T2, T3, T4 and T5) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Mean arterial pressure 2.heart rateTimepoint: 1.Baseline(immediately after arrival to operation theatre, T0) 2.Immediately after induction of anaesthesia(1 min) (T1) 3.Thereafter at 3, 5, 10 and 30 minutes post induction (T2, T3, T4 and T5) 4.immediately after laryngoscopy and scalp pin insertion (if done). | — |
Countries
India
Contacts
Public ContactSiddharth Chakraborty
All India Institute of Medical Sciences,Rishikesh
Outcome results
None listed