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Azithromycin with full mouth cleaning in pyorrhoea patients

Azithromycin as an Adjunct to One- Stage Full-Mouth Disinfection in Stage III Grade B Unstable generalised periodontitis: A Randomized Controlled Clinical Trialâ??

Status
Active, not recruiting
Phases
Phase 1Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/10/028692
Enrollment
30
Registered
2020-10-28
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K052- Aggressive periodontitis

Interventions

Intervention1: Full mouth disinfection (chlorhexidine gel and mouthwash) with azithromycin: 15 subjects will be treated with full mouth disinfection (chlorhexidine gel and mouthwash) with azithromycin

Sponsors

Sharad Pawar Dental College Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Generalized interproximal attachment loss involving at least three teeth apart from molars and �rst incisors. 2.Amount of microbial deposits inconsistent with the severity of periodontal tissue destruction. 3.Patients with a minimum number of 20 teeth. 4.Patients with clinical attachment loss and probing depths (PDs) >= 4 mm at 2 sites of a minimum of 12 teeth 5.The patients included in the study should be systemically healthy. 6.Patients with no history of periodontal therapy in the preceding 6 months or under any antibiotic therapy. 7.Patients motivated to have the therapy and willing to complete the follow-up.

Exclusion criteria

Exclusion criteria: 1.Patients with a known or suspected allergy 2.Patients who have undergone periodontal therapy in the last 6 months. 3.Patients with any systemic disorder affecting periodontal health. 4.Patients with infectious conditions other than periodontitis. 5.Chronic alcoholics 6.Patients consuming tobacco in any form and smokers. 7.Immuno-compromised and systemically-unhealthy patients. 8.Pregnant or lactating females.

Design outcomes

Primary

MeasureTime frame
Reduction in Probing Pocket depth (PPD)Timepoint: 3 and 6 months

Secondary

MeasureTime frame
Reduction in Bleeding on Probing (BOP), Gain in Clinical attachment level (CAL)Timepoint: Reduction in Bleeding on Probing (BOP), Gain in Clinical attachment level (CAL) at 3 and 6 months

Countries

India

Contacts

Public ContactDr Pavan Bajaj

Sharad pawar dental college

pavbajaj@gmail.com08412045019

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026