Comparing pain relief property of bupivacaine alone and bupivacaine with dexmedetomidine when given inside abdomen after operation of gall bladder with laparoscopic method

Comparative study of intraperitoneal instillation of bupivacaine alone and bupivacaine with dexmedetomidine for postoperative analgesia following laparoscopic cholecystectomy

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/10/028678

Enrollment

Registered

2020-10-28

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K808- Other cholelithiasis

Interventions

Intervention1: Intraperitoneal instillation of bupivacaine with dexmedetomidine in patients undergoing laparoscopic cholecystectomy for post operative analgesia.: At the end of surgery before removal

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients posted for elective laparoscopic cholecystectomy 2.ASA physical status I & II 3.BMI >18.5 &

Exclusion criteria

Exclusion criteria: 1.Patients refusal 2.Patients not satisfying above inclusion criteria 3.Allergic to study drugs 4.Pregnant or breast-feeding patient 5.Patients with cardiac,respiratory,liver and renal diseases 6.Patients with baseline heart rate 7.Patients with AV heart blocks 8.Laparoscopic cholecystectomy converted to open cholecystectomy 9.If any other surgery,combined with laparoscopic cholecystectomy in the same sitting like incisional hernia,umbilical hernia etc.

Design outcomes

Primary

Measure	Time frame
1.Post operative pain relief using visual analogue scale(0-100mm) 2.Time to first rescue analgesic 3.24 hours post operative total analgesic requirementTimepoint: All parameters will be recorded at 0,1,2,3,4,6,8,12,18 and 24 hours in post operative period	—

Secondary

Measure	Time frame
1.Haemodynamic variables(PR,MAP,SPO2) 2.Ramsay sedation score 3.ComplicationsTimepoint: All parameters will be recorded at 0,1,2,3,4,6,8,12,18,and 24 hours in post operative period	—

Countries

India

Contacts

Public ContactDr Jayita Sarkar

J.L.N. Hospital and Research Centre,Sector-9,Bhilai

drjayitaonnet@yahoo.in9407982774

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026