A study to evaluate the effect of hyperbaric oxygen therapy along with local antibiotic therapy and wound care in the healing of infected pressure ulcers.

A prospective randomised control trial to evaluate the effect of adjunctive hyperbaric oxygen therapy in the clinical and microbiological outcome of infected pressure ulcers.

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/10/028668

Enrollment

Registered

2020-10-27

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L00-L99- Diseases of the skin and subcutaneous tissue

Interventions

Intervention1: Hyperbaric Oxygen therapy(Group H): The wounds of all selected patients based on well defined inclusion criterias will be clinically evaluated and documented which includes site, du

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients above the age >18 years and 2. Patients with infected pressure ulcers as evidenced by positive gram stain/ wound cultures 3. Who give consent to take part in the study

Exclusion criteria

Exclusion criteria: Exclusion Criteria : 1. Patients who do not give consent 2. Age 60years 3.Patients with pneumothorax, COPD 4.Patients with ejection fraction less than 35 % 5.Pregnant patients, Post chemotherapy patients. 8 .Patients with ear disease seizure disorders, hereditary Spherocytosis

Design outcomes

Primary

Measure	Time frame
To compare the clinical effect of hyperbaric oxygen therapy on pressure ulcers by serially assessing change in PUSH score ( Pressure Ulcer Scale for Healing) of the wound. To compare the microbiological effect of hyperbaric oxygen therapy on pressure ulcers by serially evaluating the change in colony forming units of microorganisms isolated from the wound culture as per standard microbiological techniques Timepoint: 15 days	—

Measure

Time frame

To compare the clinical effect of hyperbaric oxygen therapy on pressure ulcers by serially assessing change in PUSH score ( Pressure Ulcer Scale for Healing) of the wound. To compare the microbiological effect of hyperbaric oxygen therapy on pressure ulcers by serially evaluating the change in colony forming units of microorganisms isolated from the wound culture as per standard microbiological techniques Timepoint: 15 days

—

Secondary

Measure	Time frame
To compare the mean duration of hospital stay in both groups.To assess the total number of patients requiring debridement in both groups Timepoint: 12 months	—

Countries

India

Contacts

Public ContactDr Haritha I

AIIMS , Rishikesh

ankit.anaes@aiimsishikesh.edu.in

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026