Comparison of two different type of fluid (normal saline versus balanced solution) in emergency neurosurgical patients.

COMPARISON OF NORMAL SALINE AND BALANCED CRYSTALLOID SOLUTION ON ACID BASE AND ELECTROLYTE STATUS IN EMERGENCY NEUROSURGICAL TRAUMA PATIENTS - A PROSPECTIVE RANDOMISED DOUBLE BLIND STUDY

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/10/028620

Enrollment

100

Registered

2020-10-26

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S068- Other specified intracranial injuries

Interventions

Intervention1: Balanced crystalloid: Balanced crystalloids will be administered to emergency neurosurgical patients posted for emergency neurosurgery. Control Intervention1: Normal Saline: Normal Sali

Eligibility

Inclusion criteria

Inclusion criteria: 1.Age group between 18 and 60 years. 2.Traumatic neurosurgical emergency patients posted for decompressive craniotomy. 3.Patients received from emergency of trauma centre with in 24hrs of injury after resuscitation.

Exclusion criteria

Exclusion criteria: 1. Patient/relative refusal. 2. Patient baseline electrolytes are outside normal range. 3. Patient on inotropic support. 4. Patient with any systemic illness like Diabetes,Hypertension. 5. Patient with end stage organ damage e.g. hepatic,renal or cardiovascular disorder. 6. Patient with polytrauma.

Design outcomes

Primary

Measure	Time frame
Acid base and electrolyte statusTimepoint: Preoperative, at end of surgery before extubation and 6 hr. postoperatively	—

Secondary

Measure	Time frame
NilTimepoint: Nil	—

Countries

India

Contacts

Public ContactDr YASHPAL SINGH

Institute of medical sciences, Banaras Hindu University

dryashacin1999@rediffmail.com9918424416

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026