None listed
Conditions
Interventions
Intervention1: Lifestyle optimisation: Diet based on valorie requirement as calculated by indirect calorimetry. plus regular exercise for 14 days prior to donor hepatectomy
Control Intervention1: cont
Sponsors
ILBS
Eligibility
Inclusion criteria
Inclusion criteria: All donors planned for donor hepatectomy and found fit in step II evaluation.
Exclusion criteria
Exclusion criteria: Patients refusing to consent for the study Donor of ALF patients. Donors undergoing left lateral hepatectomy. Donors found unfit after step I/II evaluation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage growth of liver(on basis of CT Volumetry) at post op day 7 and at 14 days follow up after donor hepatectomy between both the groups.Timepoint: Post op day 7 and 14. | — |
Secondary
| Measure | Time frame |
|---|---|
| Body composition analysis and fibroscan before and after lifestyle modification.Timepoint: 14 days and 1 day before surgery.;Intraoperative blood loss, post op stay in the hospital and complication rates between both the groupsTimepoint: Intraoperatively and then post op day 1 - 14;Post operative day of normalization of serum bilirubin and PT-INR between both the groups.Timepoint: Pst operative day 1- 14;Rates of early graft dysfunction in recipients in both the groups.Timepoint: Post operative day 1-14;Serum level of markers of liver regeneration after liver transplant in both the groups.Timepoint: 14 days and 1 day before surgery and then post operative day 1, 3 and 7.;Steatosis in both groups on basis of intra operative liver biopsy.Timepoint: Intra operative | — |
Countries
India
Contacts
Public ContactDr Anish Gupta
ILBS
Outcome results
None listed