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comparing the vitamin A Cream with drumstick plant extract gel in treatment of oral potentially malignant disorder-leukoplakia

Comparison of effectiveness of Moringa oleifera leaves extract gel [2%] with Retino A (0.1%) cream for treatment of oral leukoplakia - A double blinded randomised control trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/10/028529
Enrollment
72
Registered
2020-10-21
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C14- Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx

Interventions

Intervention1: Moringa Oleifera leaves mucoadhesive gel: Moringa Oleifera is rich in antioxidants. The extraction of active ingredients such as quercetin will be done using the process of maceration(h

Sponsors

DrAnsari Sulem Riyaz Ahmed
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Homogeneous leukoplakia of size range 2-6 cm in greatest dimension. 2.Patients above 18 years. 3.Patients who are willing to participate in this study.

Exclusion criteria

Exclusion criteria: 1.Non-homogenous leukoplakia. 2.Leukoplakia more than 6 cm in greatest dimension. 3.Leukoplakia involving tongue and floor of oral cavity. 4.Patients with any other potentially malignant disorders other than Oral leukoplakia and under treatment. 5.Pregnant and lactating females. 6.Patients who have already undergone treatment for Oral Leukoplakia (within 3 months)

Design outcomes

Primary

MeasureTime frame
Reduction in the size of lesion of oral leukoplakia.Timepoint: 1,2,3 months

Secondary

MeasureTime frame
Reduction in burning sensationTimepoint: 1,2,3 months

Countries

India

Contacts

Public ContactDr Ansari Sulem Riyaz Ahmed

Dept.of OMDR KLE Vishwanath Katti Institute of dental sciences

cshivayogi@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026