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Comparison of clonidine and dexmedtomidine as additives to the routinely used drug for spinal anaesthesia: bupivacaine in pregnant females delivering by the surgical method, commonly known as Caesarean delivery.

Intrathecal clonidine versus dexmedetomidine as adjuvants to bupivacaine in elective LSCS patients.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/10/028490
Enrollment
90
Registered
2020-10-20
Start date
Unknown
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O00-O9A- Pregnancy, childbirth and the puerperium

Interventions

Intervention1: Intrathecal clonidine versus dexmedetomidine as adjuvants to bupivacaine for postoperative analgesia, in elective LSCS patients.: 1. â??To evaluate the efficacy and safety of intratheca

Sponsors

Department of Anaesthesiology
Lead Sponsor
Department of Anaesthesia
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: All term ( >36 weeks) pregnant women who fall under the American Society of Anaesthesiologists (ASA) class 2, scheduled for elective caesarean section

Exclusion criteria

Exclusion criteria: 1. Patientâ??s refusal to participate. 2. Gestational age less than 36 weeks. 3. Active or early labour, ruptured membranes. 4. Placenta previa. 5. Patientâ??s body mass index (BMI) >35kg/m2. 6. Hypertension or pre-eclampsia. 7. Diabetes Mellitus or Gestational Diabetes. 8. Intrauterine growth restriction. 9. Any history or clinical evidence of cardiac disease. 10. Any contraindications to regional anaesthesia, such as local infection or bleeding disorders. 11. Patients falling under ASA3 and above. 12. Coagulation abnormalities.

Design outcomes

Primary

MeasureTime frame
To evaluate the efficacy and safety of intrathecal clonidine and dexmedetomidine as adjuvants to bupivacaine for postoperative analgesia. Timepoint: Intra operative monitoring of haemodynamic parameters - every 5 minutes for the first half an hour followed by every 10 minutes till the completion of surgery.

Secondary

MeasureTime frame
â??To compare their duration of post operative analgesia.Timepoint: Post operative monitoring every half an hour

Countries

India

Contacts

Public ContactGayatri Kashyap

Indira Gandhi Medical College

gi.anjna@gmail.com9418570717

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026