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To study the relationship of COVID-19 severity with blood vessels

To study the relationship of COVID-19 Severity with Arterial Stiffness: A Prospective Observational Study - COSEVAST study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2020/10/028489
Enrollment
75
Registered
2020-10-20
Start date
Unknown
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere

Interventions

Intervention1: To study if measurement of arterial stiffness using Pulse Wave velocity in mild group of COVID-19 Patients can stratify Cardiovascular risk.: To study if measurement of arterial stiffn

Sponsors

AIIMS Patna
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. RT PCR proved COVID-19 positive patients admitted in AIIMS Patna 2. Age = 18 years 3. Clinical Category of Patients 4. Participants who are willing to provide informed consent and willing to undergo the PeriScope test

Exclusion criteria

Exclusion criteria: 1. Patients with severe CAD, 2. Congestive heart failure CHF 3. Hypertension, 4. Patients on insulin, diabetic neuropathy, 5. Diabetic Keto acidosis 6. Stroke and peripheral arterial disorder 7. Pre-existing Cardiovascular disease 8. Severe Hypertension 9. Recent MI 10. Cardiac transplant within the last 12 months 11. Pregnancy 12. Patient with peripheral Edema 13. Patient with Cardiac Arrhythmia

Design outcomes

Secondary

MeasureTime frame
To determine if initial measurements and subsequent changes in arterial stiffness can project the future course of the Covid-19 patient and hence predict the grade of clinical management a confirmed Covid-19 patient would require. Timepoint: 0 Day, 2nd Day, 4th Day, 6th Day, 8th Day and 10th Day or on the day of clinical deterioration (change in category to moderate/severe) which ever is earlier.

Primary

MeasureTime frame
To study if measurement of arterial stiffness using Pulse Wave velocity in mild.moderate and severe group of COVID-19 Patients can stratify Cardiovascular risk.Timepoint: 0 Day, 2nd Day, 4th Day, 6th Day, 8th Day and 10th Day or on the day of clinical deterioration (change in category to moderate/severe) which ever is earlier.

Countries

India

Contacts

Public ContactNeeraj Kumar

AIIMS Patna

Neeraj.jlnmc@gmail.com8210104972

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026