Disinfection of Root canal using Calcium hydroxide and Sodium hypochlorite

Impact of passively placed sodium hypochlorite in a calcium hydroxide dressing on root canal disinfection and periapical tissue response: a randomized controlled trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/10/028484

Enrollment

110

Registered

2020-10-20

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K044- Acute apical periodontitis of pulpal origin Health Condition 2: I00-I99- Diseases of the circulatory system

Interventions

Intervention1: sodium hypochlorite and calcium hydroxie: Mixture of calcium hydroxide and sodium hypochlorite placed as intracanal medicament for one week Control Intervention1: calcium hydroxide: cal

Eligibility

Inclusion criteria

Inclusion criteria: pulpal diagnosis of necrosis and an apical diagnosis of symptomatic/asymptomatic apical periodontitis

Exclusion criteria

Exclusion criteria: (i) a chronic condition requiring the intake of anti-inflammatory/antibiotic drugs, (ii) tooth which cannot be isolated by rubber dam properly, (iii) a non-restorable tooth, or (iv) root canals in which patency for periapical fluid sampling cannot not be achieved

Design outcomes

Primary

Measure	Time frame
Microbial samples from root canalTimepoint: one week	—

Secondary

Measure	Time frame
periapical markersTimepoint: 4 weeks	—

Countries

India

Contacts

Public ContactVasudev Ballal

Manipal College of Dental Sciences

drballal@yahoo.com09880626167

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026