FindTrial
Sign In

Effect of lung protective ventilation on oxygenation , ventilatory parameters and inta-cranial pressure.

Correlation of oxygenation, ventilatory parameters and optic nerve sheath diameter (ONSD) to intra-operative mechanical ventilation in abdominal surgeries , comparison of recruitment manuever with conventional ventilation. A pilot randomised controlled trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/10/028465
Enrollment
60
Registered
2020-10-19
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C15-C26- Malignant neoplasms of digestive organs

Interventions

Intervention1: Lung protective ventilation: Recruitment maneuver followed by decremental PEEP trial to set optimum PEEP Control Intervention1: Conventional mechanical ventilation: PEEP 5

Sponsors

NIL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA physical status i-iii 2. Age group of 18-70 3.BMI 4. Candidates posted for upper abdominal surgeries and surgical duration expected to exceed beyond 2 hours

Exclusion criteria

Exclusion criteria: 1.Mechanical ventilation of > 1 hour within the last 2 weeks before surgery 2. Body mass index � 35 kg/m2 3. Acute respiratory failure (pneumonia, acute lung injury or acute respiratory distress syndrome) - Emergency surgery - Sepsis or septic shock - Progressive neuromuscular illness - Intra-thoracic surgery - Pregnancy - Orbital tumors - Optic neuritis - Glaucoma - Refusal to participate

Design outcomes

Primary

MeasureTime frame
Effect of periodic recruitment manuever on PaO2, P:F, driving pressure, respiratory compliance Effect of periodic recruitment manuever on ONSDTimepoint: Periodic recruitent manuever will be done to.set optimum PEEP at 30, 60, 120 th minutes after induction of general anesthesia—

Secondary

MeasureTime frame
Not applicableTimepoint: Not applicable—

Countries

India

Contacts

Public ContactDr Mahajan Jitendra Subhash

Dr. B.R.A.I.R.C.H. AIIMS New Delhi

sushmabhatnagar1@gmail.com9811326453

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026