Clinical study to evaluate the effect of Ayurveda intervention as a prophylaxis for COVID-19 in Healthcare workers

“Pre-Exposure, Ayurveda Prophylaxis For COVID-19 In Healthcare Workers: A Pragmatic, Risk Stratified, Randomized Clinical Trial ? - PRASACT

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/10/028424

Enrollment

200

Registered

2020-10-15

Start date

Unknown

Completion date

Unknown

Last updated

2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Classical Ayurveda Intervention (Ahara-Vihara-Aushadha): Sudarshana Ghana Vati (0-1-1) AF (after food),Dhanvantaram Gutika (0-1-1) AF (after food) Chywanaprasha 1 tsp twice daily at 9 a

Eligibility

Inclusion criteria

Inclusion criteria: 1.Consenting Healthcare Workers at Aster CMI Hospital 2.HCWs with Active Asthma/ Bronchitis/ COPD but not on any internal medication. 3.Willingness/Consent to participate in the Trial 4.18 years and older

Exclusion criteria

Exclusion criteria: 1.Active COVID-19 disease 2.Prior COVID-19 disease 3.Pregnant Women and Breast feeding Mother 4.Children Below 1 year 5.HIV 6.Organ Donors 7.Patients with Organ Transplant 8.Participation in any other COVID-19/COPD Trial 9.Patients with Active Malignancy 10.Patients with Chronic Kidney with GFR 11.Patients with Bleeding Disorders 12.Patients with Active Upper or Lower Respiratory Tract Infection Disorders on any Allopathy Internal Medication 13.Health care workers who are on HCQ medication

Design outcomes

Primary

Measure	Time frame
% Of staff members who develop NCMP Stages, by stage, within 1month/2months/3months of enrolment into study. COVID-19-free survivalTimepoint: 3 months	—

Secondary

Measure	Time frame
Incidence of confirmed SARS-CoV-2 detection, Incidence of possible COVID-19 symptoms , WHO Ordinal Scale, Risk Rating at Start, 3 months , or Withdrawal, Incidence of Hospitalization for COVID-19 or death , QoL(Quality of Life), Stress Scale, Ayurveda Swasthya Lakshanas, Biomarkers(at start and end of study;Blood Immune Cell Count(leukocyte, neutral, lymphocyte counts and absolute lymphocyte) Serum Inflammatory Markers(c-reactive protein) ESR, Platelet, Serum Creatinine Timepoint: 3 months	—

Measure

Time frame

Incidence of confirmed SARS-CoV-2 detection, Incidence of possible COVID-19 symptoms , WHO Ordinal Scale, Risk Rating at Start, 3 months , or Withdrawal, Incidence of Hospitalization for COVID-19 or death , QoL(Quality of Life), Stress Scale, Ayurveda Swasthya Lakshanas, Biomarkers(at start and end of study;Blood Immune Cell Count(leukocyte, neutral, lymphocyte counts and absolute lymphocyte) Serum Inflammatory Markers(c-reactive protein) ESR, Platelet, Serum Creatinine Timepoint: 3 months

—

Countries

India

Contacts

Public ContactDr Zankhana Buch

AyurVAID Hospitals

zankhana_buch@ayurvaid.com

Outcome results