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Comparative study of effects of ketamine gargles vs lignocaine gargles in upper gastrointestinal scopies for prevention of post operative sore throat, coughing and change in voice

The study of effect of ketamine gargles vs lignocaine gargles for prevention of post operative sore throat, coughing & change in voice in upper gastro-intestinal scopies: A Randomised Control Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/10/028411
Enrollment
70
Registered
2020-10-14
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K319- Disease of stomach and duodenum, unspecified

Interventions

Intervention1: Ketamine Gargles: ketamine gargles (3mg/kg diluted in ns+ total 30ml) will be given to the patient prior to the procedure for 60 seconds and post procedure sore throat, coughing and cha

Sponsors

Shri Krishna Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: a) Patients ASA (American Society Of Anesthesiology) 1-3 status b) Age 18-60 yrs c) Patients undergoing upper gastro intestinal scopy procedures under general anesthesia

Exclusion criteria

Exclusion criteria: a) Patients refusal & uncooperative patients b) Anticipated difficult airway c) History of preoperative sore throat & asthma d) Patients of known allergy to study drug e) Patient with upper respiratory tract infection f) intubated patients

Design outcomes

Primary

MeasureTime frame
Post operative sore throat, coughing and hoarseness of voice will be observedTimepoint: immediate post operative, at 1 hour, at 4 hour, at 24 hour

Secondary

MeasureTime frame
less intra operative and post operative discomfort, less need of analgesics, improved patient satisfaction, decrease in length of stay in hospitalTimepoint: immediate post operative, at 1 hour, at 4 hour, at 24 hour

Countries

India

Contacts

Public ContactDr Sunny Mevcha

H M Patel Centre for Medical Care and Education

madhavic@charutarhealth.org9427084963

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026