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In this study we will compare the effect of 2 drugs dexmedetomidine and clonidine as an additive to bupivacaine in spinal anaesthesia for patients undergoing abdominal hysterectomy

A prospective randomized comparative study of Dexmedetomidine and clonidine as an adjuvant to intrathecal bupivacaine in patients undergoing total abdominal hysterectomy.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/10/028408
Enrollment
78
Registered
2020-10-14
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Dexmedetomidine: 1ml ampoule of 50µg Dexmedetomidine is diluted to 2ml by using 1 ml of normal saline. Out of which 0.2 ml ( Dose -5µg) of dexmedetomidine will be taken. The Group W

Sponsors

Rupesh Choudhary
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: INCLUSION CRITERIA 1) patients undergoing total abdominal hysterectomy willing to give consent for study 2) age between 35-60 years. 3) ASA I and ASA II patients

Exclusion criteria

Exclusion criteria: EXCLUSION CRITERIA 1) Hypersensitivity to the study drugs 2) Patients having any bleeding disorders 3) Patient having decreased platelet counts 4) Patients having spinal column deformities 5) Patients undergone any spine surgery 6) Infection at local site 7) Patients on beta blockers

Design outcomes

Primary

MeasureTime frame
Total duration of postoperative analgesiaTimepoint: Every 30 minutes after giving drug till the effect of drug wean off.—

Secondary

MeasureTime frame
1 Onset and duration of sensory and motor block 2 Two segment regression time 3 Changes in hemodynamic parameters intraoperatively â?? heart rate (HR), noninvasive blood pressure (NIBP), and oxygen saturation (SPO2). 4 Side effects of any of the drug used. Timepoint: Every 30 minutes after giving drug till the effect of drug weans off—

Countries

India

Contacts

Public ContactRUPESH CHOUDHARY

INDIRA GANDHI MEDICAL COLLEGE

aparnasharmaraina@gmail.com9418083224

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026