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A Comparative Study Of Dexmedetomidine Versus Nalbuphine For Postoperative Pain Treatment

â??A Comparative Study Of Bolus Dexmedetomidine Versus Nalbuphine As Rescue Analgesia AfterAbdominal Hysterectomyâ??

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/10/028394
Enrollment
90
Registered
2020-10-13
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N800- Endometriosis of uterus

Interventions

Intervention1: Dexmedetomidine: Intravenous Bolus dose of Dexmedetomidine 1mcg/kg for rescue analgesia over10 minutes Control Intervention1: nalbuphine: Intravenous nalbuphine 10 mg Bolus as rescue a

Sponsors

Akbar Hasan
Lead Sponsor
Dr dulal kishun soren
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Female patients of age group 40 to 55 years ASA grade 1and2. Patients planned for abdominal hysterectomy under spinal anaesthesia with bupivacaine 0.5%hyperbaric. Duration of surgery around 60 to 90 minutes

Exclusion criteria

Exclusion criteria: Patients allergic to Dexmedetomidine or paracetamol. Cardiac diseases like heart block arrhythmia patients on drugs such asCCB ACE inhibitors Alfa adrenergic agonists. Pregnant patients surgery less than one hour or more than 2hours,gastric or peptic ulcer disease. Blood coagulation abnormalities. Impaired liver and kidney function patients. Hypertensive patients patients having BMI >30

Design outcomes

Primary

MeasureTime frame
Dexmedetomidine would be better rescue analgesic compared to nalbuphine in acute pain after abdominal hysterectomyTimepoint: 2months

Secondary

MeasureTime frame
Dexmedetomidine may be used as rescue analgesic routinely in post operative painTimepoint: 2months

Countries

India

Contacts

Public ContactDrDulal kishun soren

VIMSAR

dulalsoren@gmail.com9437254980

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026