Role of Omega 3 fatty acid in etiopathogenesis of Depression and trial of two drugs: flax seed oil and Ashwagnadharishta in its management

Role of Omega 3 fatty acids in aetiopathogenesis of Depression (Chittavasada) & evaluation of Atasi (Linum usitatissimum Linn) as adjuvant to Ashwagandharishta in its management

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/10/028383

Enrollment

130

Registered

2020-10-13

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Major Depression

Interventions

Intervention1: Flax seed oil Ashwagandharishta: to evaluate the anti depressant effect of flax seed oil and Ashwagandharishta Intervention2: Flax seed oil: 10 ml twice a day mixing with food Intervent

Eligibility

Inclusion criteria

Inclusion criteria: Patients fulfilling the Diagnostic criteria DSM IV of major depressive disorder and age above 15 & below 70 years will be included in the present study.

Exclusion criteria

Exclusion criteria: 1) Patients below age 15 years and above 60 years will be excluded. 2) Those having symptoms due to direct physiological effects of substance (e.g. drug abuse, a medication) or a general medical condition (e.g. hypothyroidism) also not included.

Design outcomes

Primary

Measure	Time frame
Montgomery Asberg Depression Rating Scale Beck Depression Inventory Hamilton Rating Scale for Depression Serum Cortisol HsCRP Timepoint: 0-60 days	—

Secondary

Measure	Time frame
Hamilton Anxiety Rating Scale DASS 21Timepoint: 0-60days	—

Countries

India

Contacts

Public ContactDr Ila Tanna

Chaudhary Brahm Prakash Ayurved Charak Sansthan, IPGT & RA, GAU, Jamnagar

drharimohan.chandola@gmail.com8826946988

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026