Role of local Ayurveda therapy along with certain oral drug in the management of Presbyopia

A Randomized Clinical study to evaluate the efficacy of Bibhitakadi Ghrita Tarpana and Ayastha Triphala with Ghrita as oral intake in the management of Timira w. s. r. to Presbyopia

Status

Active, not recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/10/028381

Enrollment

Registered

2020-10-13

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H524- Presbyopia

Interventions

Intervention1: Bibhitakadi ghrita Tarpana: Tarpana Protocol Purva karma: Netra parisheka with 50-60 ml of Triphaladi kwatha in morning for 5 days for Aama pachana and Nasya with Anu taila 6 drops in

Eligibility

Inclusion criteria

Inclusion criteria: i) Patients willing to participate in this trial through written informed consent ii) Patients who are 35 years of age and from either sex ii) Patients having specific symptoms of prathama and dwitiya patalagata timira. iii) Early to moderate presbyope determined by screening monocular best-corrected distant visual acuity (VA)

Exclusion criteria

Exclusion criteria: i) Patients with active ocular infection at visit 1 (bacterial, viral or fungal), positive history of an ocular herpetic infection, preauricular lymphadenopathy, or ongoing, active ocular inflammation (eg, moderate to severe blepharitis, allergic conjunctivitis, peripheral ulcerative keratitis, scleritis, uveitis), moderate to severe dry eye in either eye. ii) Patients with clinically significant abnormal lens findings (eg cataract) including early lens changes and/or any evidence of media opacity in either eye iii) Patients having intraocular pressure (IOP) that is less than 5 millimeters of mercury (mmHg) or greater than 22 mmHg in either eye documented at visit 1, or have a prior diagnosis of ocular hypertension or glaucoma or currently being treated with any type of topical IOP lowering (glaucoma) medication at visit 1. iv) Patients who have abnormal findings on dilated fundus exam in either eye on visit 1 or a known history of retinal detachment or clinically significant retinal disease in either eye.

Design outcomes

Primary

Measure	Time frame
To evaluate and compare the efficacy of Bibhitakadi Ghrita Tarpana and Aystha Triphala with Ghrita as oral intake in the management of Timira w. s. r. to Presbyopia Timepoint: 45 days	—

Secondary

Measure	Time frame
Any adverse event reported voluntarily, observed or enquire Timepoint: 45 days	—

Countries

India

Contacts

Public ContactDr Sanjeev Sharma

National institute of Ayurveda

profsanjeevhp@gmail.com9418079691

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026