To check the pain relieving efficacy of dexmedetomidine in above collar bone brachial plexus block (usg guided) when given perineurally versus intravenous dexmedetomidine as an adjuvant to ropivacaine versus when ropivacaine is given alone in adult patients undergoing upper limb surgery

Comparison of analgesic efficacy of dexmedetomidine as adjuvant to ropivacaine in supraclavicular brachial plexus block (usg guided) when administered perineurally versus intravenous versus when ropivacaine is given alone in adult patients undergoing upper limb surgery

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/10/028270

Enrollment

105

Registered

2020-10-07

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Control Intervention1: Ropivacaine alone or with dexmedetomidine iv or perineurally: 0.5% ropivacaine 28ml plus normal saline(0.9%) 2ml perineurally along with 30 ml NS intravenous infusion over 1 hou

Eligibility

Inclusion criteria

Inclusion criteria: ALL PATIENTS UNDERGOING UPPER LIMB SURGERY OF LESS THAN 2 HRS BETWEEN AGE GROUP OF 18 TO 60 YEARS, BMI BELOW 30, BELONGING TO ASA 1 AND 2 AND HAVING ALL ROUTINE LAB TEST WITHIN NORMAL RANGE WITH FREE FROM ANY ACUTE OR CHRONIC SYSTEMIV ILLNES

Exclusion criteria

Exclusion criteria: 1. ANY PATIENT HAVING HYPERSENSITIVITY OR CONTAINDICATION TO ROPIVACAINE AND DEXMEDETOMODINE. 2. LOCAL PATHOLOGY AT THE SITE OF INJECTION OR DISABILITY LIMITING THE PERFORMANCE OF BLOCK 3. PREGNANT , LACTATING MOTHER, DIABETIC PATIENTS, NEUROLOGICAL DEFICIT IN OPERATIVE LIMB. 4. PATIENT WITH CHRONIC PAIN OR ON LONG TERM ANALGESIC

Design outcomes

Primary

Measure	Time frame
Primary Outcome of our study is onset of sensory block, duration of sensory block, duration of analgesia during comparison between analgesic efficacy of Dexmedtomidine as adjuvant to ropivacaine in supraclavicular block (USG guided) when administred perineurally versus intravenous versus when ropivacaine given alone in adult patients undergoing upper limb surgery.Timepoint: VAS Score analysis, BP, heart rate before procedure, at the time of procedure and 24 hrs monitoring of Vitals and duration of sensory and motor block.	—

Measure

Time frame

Primary Outcome of our study is onset of sensory block, duration of sensory block, duration of analgesia during comparison between analgesic efficacy of Dexmedtomidine as adjuvant to ropivacaine in supraclavicular block (USG guided) when administred perineurally versus intravenous versus when ropivacaine given alone in adult patients undergoing upper limb surgery.Timepoint: VAS Score analysis, BP, heart rate before procedure, at the time of procedure and 24 hrs monitoring of Vitals and duration of sensory and motor block.

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Secondary

Measure	Time frame
Secondary Outcome is onset of motor block, duration of motor block, compare post-operative rescue analgesic (tramadol, diclofenac) consumption in first 24 hours, Any changes inNIBP,PR.SpO2in first 24 hour ,Patientâ??s satisfaction score ,Any complications / adverse effects/side effects of block in term of above mentioned three groups after administering block . Timepoint: VAS Score analysis, BP, heart rate before procedure, at the time of procedure and 24 hrs monitoring of Vitals and duration of sensory and motor block.	—

Measure

Time frame

Secondary Outcome is onset of motor block, duration of motor block, compare post-operative rescue analgesic (tramadol, diclofenac) consumption in first 24 hours, Any changes inNIBP,PR.SpO2in first 24 hour ,Patientâ??s satisfaction score ,Any complications / adverse effects/side effects of block in term of above mentioned three groups after administering block . Timepoint: VAS Score analysis, BP, heart rate before procedure, at the time of procedure and 24 hrs monitoring of Vitals and duration of sensory and motor block.

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Countries

India

Contacts

Public ContactDR VINAY KUMAR SHARMA

DR S.N. MEDICAL COLLEGE, JODHPUR

takml88@gmail.com9309087757

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026