Skip to content

to see the effect of two doses of dexmedetomidine on increased bp and pulse rate during putting a tube in general anaesthesia

Comparison of two different dose of intravenous dexmedetomidine in attenuating hemodynamic response to laryngoscopy and endotracheal intubation in elective general surgeries under General Anaesthesia,A Randomized Double Blind Interventional Study,S.M.S. Medical College, Jaipur during 2019-2020.

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/10/028262
Enrollment
60
Registered
2020-10-07
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: R00-R99- Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

Interventions

Intervention1: Injection dexmedetomidine 0.5mcg/kg: Group A will receive Injection dexmedetomidine 0.5mcg/kg once diluted to 20 ml normal saline as i.v.infusion over 10 min,10 min prior to intubation

Sponsors

Department of anesthesiologySMS Medical college Jaipur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA class 1(without any comorbid condition) and 2(with controlled comorbid condition) patient undergoing elective general surgeries under general anaesthesia. Patient who give informed written consent.

Exclusion criteria

Exclusion criteria: Patient unable to understand study protocol or refused to take part in it. Patient of ASA class 3,4,5. Patient on beta blockers, antidepressants,anxiolytics, anticonvulsant, antipsychotic. Patient with physical dependence on narcotics, known drug allergy to dexmedetomidine. Patient with anticipated difficult airway or those in whom laryngoscopy time exceeded 15 seconds

Design outcomes

Secondary

MeasureTime frame
To compare the effect on induction dose of propofol with two doses of dexmedetomidine. To see any adverse effectsTimepoint: Adverse effects at any time of surgery.

Primary

MeasureTime frame
To compare the effect of two different doses of intravenous dexmedetomidine at heart rate and other hemodynamic response like SBP,DBP,MAP.Timepoint: From baseline to 1,3,5,10 min post intubation

Countries

India

Contacts

Public ContactDr Shriphal Meena

SMS medical college and attached group of hospital Jaipur.

dr.shriphal@gmail.com9928350391

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026