Health Condition 1: H251- Age-related nuclear cataract
Conditions
Interventions
Intervention1: Prednisolone 1% eye drop: 6 times for one week, tapered for 6 weeks
Control Intervention1: Preserved triamcinolone acetonide 6 mg in 0.3 ml: Given sub-conjunctivaly
Sponsors
Aravind Eye Hospital and Postgraduate Institute of Ophthalmology
Eligibility
Inclusion criteria
Inclusion criteria: 1) Patients undergoing topical phacoemulsification with foldable IOL implantation 2) Senile cataract 3) Axial length of 20.5 to 25mm 4) Staying within 100 kms from base hospital and willing for follow up
Exclusion criteria
Exclusion criteria: 1) Age 2) Diabetes Mellitus of more than 5 years or those with retinopathy 2) Uncontrolled systemic illness 3) Advanced cataract (BCVA 3/60 or less) 4) NSIV, Posterior polar, subluxated , traumatic, complicated and developmental cataract 5) Pregnant and lactating women 6) Patients with mental illness 7) Non visualization of fundus 8) CDR of 0.7 & more 9) IOP of 21 & above 10) Glaucoma 11) Family history of glaucoma 12) H/O steroid responsiveness 13) On systemic steroids for asthma, rheumatoid arthritis or other illness 14)Corneal diseasess 15) Associated ocular comorbidity (ARMD, pseudo exfoliation, small pupil (5mm or less), floppy iris, corneal opacity, macular scar, epiretinal membrane, retinal detachment, uveitis, shallow anterior chamber) 16)Any intraoperative complications (PCR , ZD , Nucleus drop, Vitreous loss)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Level of Anterior chamber inflammation 2.Incidence of Cysteriod macular edema 3.Incidence of raised intra oclular pressure, glaucoma due to steroids Timepoint: 9 months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Visual outcome 2. Inflammation break through requiring topical steroidsTimepoint: 9 months | — |
Countries
India
Contacts
Public ContactDrMadhu Shekhar
Aravind Eye Hospital and Postgraduate Institute of Ophthalmology
Outcome results
None listed