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We are here to compare the use of IV magnesium sulphate and bupivacaine scalp block to reduce the frequent change in blood pressure and heart rate in patients undergoing head surgery under general anaesthesia.

Comparison of intravenous magnesium sulphate and scalp block in attenuating hemodynamic response following skull pin application in patients undergoing craniotomy under general anaesthesia.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/10/028199
Enrollment
60
Registered
2020-10-01
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G998- Other specified disorders of nervous system in diseases classified elsewhere

Interventions

Intervention1: IV Magnesium sulphate to be given 10 min prior to scalp pin insertion: Dose-50mg/kg magnesium sulfate in 100ml Normal saline. Frequency route of administration-intravenous given once. D

Sponsors

ABVIMS and Dr RML Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA physical status I and II. Scheduled for elective craniotomies

Exclusion criteria

Exclusion criteria: 1.Emergency surgeries 2.Intracranial aneurysm surgery. 3.History of magnesium sulphate consumption or allergy. 4.Allergy to bupivacaine. 5.Renal and Hepatic disease.

Design outcomes

Primary

MeasureTime frame
MAP and HRTimepoint: Baseline,at the time of pin insertion,5s,10s,30s,60s,120s,180s,300s,10min,15min and 30min after pin insertion.—

Secondary

MeasureTime frame
1.To look for any need of rescue drug used for attenuating hemodynamic response(0.5mg/kg propofol) 2.Adverse effect of drugs.Timepoint: After30s,60s,90s,120s,180s,300s,15min and 30min if patients seems to be hemodynamically unstable—

Countries

India

Contacts

Public ContactDr Astha Sahu

ABVIMS and Dr RML Hospital New Delhi

namitaarora16@yahoo.com9868219619

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026