Health Condition 1: R652- Severe sepsis
Conditions
Interventions
Intervention1: Dopamine infusion: Dose-6.7�¼g/kg/min,13.4�¼g/kg/min, 20�¼g/kg/min
Frequency-
starting dose -6.7�¼g/kg/min
to be hiked every 10 minutes depending on response
Hiked maximum 2
Sponsors
Guru Gobind Singh Medical College And Hospital Faridkot
Eligibility
Inclusion criteria
Inclusion criteria: 1.Children in fluid refractory hypotensive cold septic shock, 2.Children�2months to�14 months 3.Consent given by parents/guardians
Exclusion criteria
Exclusion criteria: Age less tha 2 months Age more than 14 years Pre existing heart disease or rhythm disturbance On vasoactive agent at the time of screening Raised intracranial pressure Known immune compromised state Severe Acute malnutrition Chronic renal disease Refusal of consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare efficacy of dopamine versus epinephrine in resolution of shock within first hour of resuscitation and at 6 hours of resuscitationTimepoint: Baseline 1 hour of resuscitation 6 hours of resuscitation | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare all cause mortality ,length of picu stau,length of mechanical ventilation,with dopamine versus epinephrine when used as first line agentTimepoint: Till Hospital stay;To compare the incidence of adverse events like arrhythmias,arterial gangrene in two groupsTimepoint: Till Hospital stay | — |
Countries
India
Contacts
Public ContactDrSeema Rai
Guru Gobind Singh Medical College And Hospital Faridkot
Outcome results
None listed