Prospective randomized controlled trial comparing the efficacy 2 different regional blocks delivered as multiple drug injections to the chest wall for management of postoperative pain in patients undergoing cardiac surgery through midline sternotomy

Prospective randomized controlled trial comparing the efficacy of a novel thoracic interfascial plane block( sub-pecto- interfascial block) with erector spinae plane block in post operative pain management in patients undergoing cardiac surgery through midline sternotomy

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/10/028184

Enrollment

Registered

2020-10-01

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I251- Atherosclerotic heart disease of native coronary artery

Interventions

Intervention1: Sub-pecto- interfascial Plane block, erector spinae plane block: ultrasound guided either of the above mentioned regional blocks will be given to patients in the intervention arm Contr

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing coronary artery bypass grafting surgery will be included in the study

Exclusion criteria

Exclusion criteria: 1. Patients with known coagulopathy (INR > 2.5) 2. Known allergy to local anaesthetics 3. Patients with psychiatric disorders 4. Patients who are alcohol dependent 5. Emergency surgery

Design outcomes

Primary

Measure	Time frame
Total consumption of fentanyl in first 24 hours postoperativelyTimepoint: Initial 24 hours postoperatively	—

Secondary

Measure	Time frame
C reactive protein level (CRP) levelTimepoint: pre-operatively and 24 hours post surgery;NRS score assessmentlTimepoint: 2,4,6,8,12 and 24 hrs after surgery by ICU nurse;Peak inspiratory flow ratesTimepoint: Initial 24 hours postoperatively;Serum Cortisol levelTimepoint: pre-operatively and 24 hours post surgery;Serum prolactin levelTimepoint: pre-operatively and 24 hours post surgery;Total length of ICU stayTimepoint: Total length of ICU stay;Total rescue analgesia received in the PACU/ICUTimepoint: Initial 24 hours postoperatively	—

Measure

Time frame

C reactive protein level (CRP) levelTimepoint: pre-operatively and 24 hours post surgery;NRS score assessmentlTimepoint: 2,4,6,8,12 and 24 hrs after surgery by ICU nurse;Peak inspiratory flow ratesTimepoint: Initial 24 hours postoperatively;Serum Cortisol levelTimepoint: pre-operatively and 24 hours post surgery;Serum prolactin levelTimepoint: pre-operatively and 24 hours post surgery;Total length of ICU stayTimepoint: Total length of ICU stay;Total rescue analgesia received in the PACU/ICUTimepoint: Initial 24 hours postoperatively

—

Countries

India

Contacts

Public ContactRashmi Singh

All India Institute of Medical Sciences, New delhi

archymd@gmail.com9968173872

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026