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Effects of Traditional Nasal Saline (Simply Saline) and a Novel Nasal Salt on Aerosol Cleansing

Nasal Calcium Salts for Clearing Exhaled Bioaerosols in healthy volunteers and in asymptomatic and midly symptomatic SARS COV 2 patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/09/028084
Enrollment
80
Registered
2020-09-28
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere

Interventions

Intervention1: Nasal mist calcium salts: 100 mg through Nasal administration once for 5 minutes Control Intervention1: Normal Saline: 100 mg through Nasal administration once for 5 minutes

Sponsors

Bangalore Baptist Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Phase1: . Health care workers or the general public . Willing for nasal spray treatment Phase2: Asymptomatic or mild COVID case with a Positive nasopharyngeal swab for SARS-Cov-2 (RT-PCR) not more than two weeks

Exclusion criteria

Exclusion criteria: Phase1: Any symptoms suggestive of SARS-Cov-2 Phase2: . Nasal spray administered less than 12 hours before the study . active treatment with medications with a known side effect of dry mouth . current or prior mucosal head and neck cancer treatment, . acute or chronic upper aerodigestive tract infection,

Design outcomes

Primary

MeasureTime frame
Exhaled bioaerosol count (particles per liter of air)Timepoint: Exhaled bioaerosol count (particles per liter of air)@ 15,30,45 minutes and 1Hr—

Secondary

MeasureTime frame
Nasal irritationTimepoint: Nasal irritation @ 15,30,45 minutes and 1Hr—

Countries

India

Contacts

Public ContactDr Carolin Elizabeth George

Bangalore Baptist Hospital

carolinelizabethj@gmail.com9972156838

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026