To compare the action of tranexamic acid and Adrenaline with lignocaine on blood loss, blood pressure, heart rate when given at site of lumbar spine surgery

Effect of local infiltration of tranexamic acid and lignocaine with adrenaline on intraoperative hemodynamics and hemostasis during elective lumbar spine surgeries

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/09/028080

Enrollment

Registered

2020-09-28

Start date

Unknown

Completion date

Unknown

Last updated

2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M472- Other spondylosis with radiculopathy Health Condition 2: M472- Other spondylosis with radiculopathy Health Condition 3: M479- Spondylosis, unspecified

Interventions

Intervention1: Effect of local infiltration of tranexamic acid and lignocaine with adrenaline on intraoperative hemodynamics and hemostasis in elective lumbar spine surgeries: Infiltrating one gram of

Eligibility

Inclusion criteria

Inclusion criteria: ASA physical status 1 and 2 Scheduled for elective spine surgery

Exclusion criteria

Exclusion criteria: ASA Physical status III and IV Coagulation abnormalities Patients on any anticoagulant and antiplatelet medications Pregnancy and lactation

Design outcomes

Primary

Measure	Time frame
Comparing the effect of local infiltration of tranexamic acid and lignocaine with adrenaline on intraoperative hemodynamics and hemostasis in elective lumbar spine surgeriesTimepoint: Comparing the effect of local infiltration of tranexamic acid and lignocaine with adrenaline on intraoperative hemodynamics and hemostasis in elective lumbar spine surgeries from incision of surgery till skin closure	—

Measure

Time frame

Comparing the effect of local infiltration of tranexamic acid and lignocaine with adrenaline on intraoperative hemodynamics and hemostasis in elective lumbar spine surgeriesTimepoint: Comparing the effect of local infiltration of tranexamic acid and lignocaine with adrenaline on intraoperative hemodynamics and hemostasis in elective lumbar spine surgeries from incision of surgery till skin closure

—

Secondary

Measure	Time frame
NilTimepoint: Nil	—

Countries

India

Contacts

Public ContactJananee V B

Kempegowda institute of medical science

madhavareddy.r@gmail.com9379094790

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026