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Variation in biochemical parameters in COVID-19 infection

Role of biochemical markers in COVID-19 infection

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2020/09/028069
Enrollment
150
Registered
2020-09-28
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere

Interventions

None listed

Sponsors

Sri Ramachandra Institute of Higher Education Research Institute SRIHERDU
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: o Data of Individuals tested with Positive RT- PCR/ viral nucleic acid test for COVID-19 will be accessed o Patients Presenting with mild / No symptoms (Isolation ward participants data will be accessed) o Patients Presenting with moderate/ severe symptoms of COVID â?? 19 (ICU participants data will be accessed)

Exclusion criteria

Exclusion criteria: Following Records of investigations will not be accessed: o Data of Individuals with Liver disease, Rheumatoid arthritis, Renal disease & cardiac disease will not be accessed. o Reports presenting with any other bacterial infections will not be accessed o Reports of Pregnant women and age below o Data of Patients presenting with dengue, malaria infections will not be acquired.

Design outcomes

Primary

MeasureTime frame
To understand the biochemical alterations and prognosis of the COVID â?? 19 pandemic infectionTimepoint: 6 - 7 months

Secondary

MeasureTime frame
Elevated LDH values were associated with 6- fold increased odds of severe COVID-19 infection. Hyper ferritinemia directly contributes to immune-suppressive and pro-inflammatory effects, and contributing to the cytokine storm and increased severity of the disease. Higher levels of hs-CRP can be a predictive marker in determining inflammatory response in COVID â?? 19.Timepoint: 6 - 7 months

Countries

India

Contacts

Public ContactS Sowmiya

Sri Ramachandra institute of Higher Education & Research, SRIHER(DU)

ksowmya@sriramachandra.edu.in

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026