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A STUDY ON THE FACTORS INVOLVED IN THE FORMATION OF HEART BLOOD VESSEL INTERCONNECTIONS IN HIGH BLOOD PRESSURE AND NORMAL BLOOD PRESSURE PATIENTS SUFFERING FROM HEART BLOOD VESSEL BLOCKS

A STUDY ON THE FACTORS AFFECTING DEVELOPMENT OF CORONARY COLLATERALS IN HYPERTENSIVE AND NON-HYPERTENSIVE PATIENTS DURING OBSTRUCTIVE CORONARY ARTERY DISEASE

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2020/09/028062
Enrollment
100
Registered
2020-09-25
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I251- Atherosclerotic heart disease of native coronary artery

Interventions

Intervention1: level of Vasculo Endothelial Growth Factors: The level of Vasculo Endothelial Growth Factors in the blood serum, collateral scores based on gender will be correlated with collaterals fo

Sponsors

Indian Council of Medical Research ICMR
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patient underwent coronary angiography in VMKV Medical College & Hospital and VIMS Hospital, Salem from 2019 to 2020 those with >50% of stenosis

Exclusion criteria

Exclusion criteria: Patients those with <50% diameter stenosis those who received nitrates or calcium channel blockers immediately before the procedure are excluded from the study

Design outcomes

Primary

MeasureTime frame
The level of Vasculo Endothelial Growth Factors in the blood serum, collateral scores based on gender will be correlated with collaterals formed in hypertensive and non-hypertensive patients. Changes in the endothelial thickening, arrangement of smooth muscles and internal elastic lamina are studied in detail in autopsy specimen with atherosclerotic lesion to explain the factors affecting collateral formation.Timepoint: 2 years—

Secondary

MeasureTime frame
The factors affecting the formation of collaterals once found out, the study will be further extended to large number of population from different parts of TamilNaduTimepoint: 5 years—

Countries

India

Contacts

Public ContactDr B Senthil Kumar

Vinayaka Missions Kirupananda Variyar Medical College & Hospitals

skdrchinu88@gmail.com9894398677

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026