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comparing two different methods of giving drug magnesium sulfate for treating after surgery sore throat

Comparison of Effectiveness of intravenous route versus nebulization of Magnesium sulphate for postoperative sore throat and hoarseness : a Randomised Comparative Clinical study.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/09/028047
Enrollment
140
Registered
2020-09-25
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Magnesium Sulphate through Intravenous route: Magnesium Sulphate through Intravenous Route 10mg/kg,single shot over period of 20 Minutes slowly at onset of surgery for Postoperative pr

Sponsors

rajarajeswari medical college and hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Adult patients between 18-65 yr of age of either sex. 2. ASA status I and II 3. Undergoing unilateral PCNL and RIRS surgeries.

Exclusion criteria

Exclusion criteria: 1. Patients refusing to participate in the study 2. Patient with uncontrolled hypertension, diabetes, cardio-respiratory disorders, neuro-psychiatric disorders, hepatic or renal dysfunction. 3. Surgery involving the oral cavity, nasopharynx, larynx and neck regions. 4. History of preoperative sore throat, common cold, anticipated difficult airway. 5. Pregnant or lactating mothers. 6. Recent use of antiinflammatory drugs 7.Allergic to study drug

Design outcomes

Primary

MeasureTime frame
Nebulised Magnesium Sulphate is better compared to Intravenous Magnesium SulphateTimepoint: 3 months

Secondary

MeasureTime frame
Safety profile of Magnesium Sulphate at 10mcg/ kg both Intravenously and NebulisationTimepoint: 3 months

Countries

India

Contacts

Public ContactDr Rashmi

RajaRajeswari Medical College and Hospital

rashmi.rp16@gmail.com9986665368

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026