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A clinical trial to compare the effects of two drugs, Articaine and Lidocaine in pain control during dental treatment, assessed through different methods

COMPARATIVE EVALUATION OF ANESTHETIC EFFICACY OF 4 % ARTICAINE (INFILTRATION TECHNIQUE) AND 2% LIDOCAINE (INFERIOR ALVEOLAR NERVE BLOCK) FOR PULP THERAPY IN PRIMARY MANDIBULAR MOLARS THROUGH PAIN AND BEHAVIORAL SCALES AND PHYSIOLOGICAL PARAMETERS- A RANDOMIZED, CROSS OVER, SPLIT MOUTH DESIGN STUDY

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/09/027998
Enrollment
52
Registered
2020-09-23
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis

Interventions

Intervention1: 4 % Articaine Buccal Infiltration: 4% Aricaine (68 mg) with 1:100000 Epinephrine (0.017mg) 1.7 ml Buccal Infiltration Technique Control Intervention1: 2% Lidocaine Inferior Alveolar Ner

Sponsors

Anu V F
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Cooperative children between the age group of 6-10 years with Frankel behavior rating scale (FBRS) score of 3 or 4 having bilaterally involved vital primary mandibular molars(symptom free, deep carious lesion approaching or encroaching the pulp/ cariously exposed pulp associated with spontaneous pain) indicated for pulp therapy ,The tooth should have had no history of infection (abscess) or swelling and no evidence of periapical pathosis or soft tissue infection/ inï¬â??ammation near site of injection.

Exclusion criteria

Exclusion criteria: Medically compromised patients- with known history of cardiovascular, hepatic, epilepsy, renal disease, uncontrolled diabetes and patients on antiplatelet/anticoagulant medications. ,Patients with known history of plasma cholinesterase deficiency and patients known to be allergic to amide local anesthetics ,Evidence of infection near the proposed injection site as this might affect the ef�cacy of local anaesthesia. ,Non vital teeth and teeth other than primary mandibular molars. ,Intake of analgesics on the day of treatment.

Design outcomes

Primary

MeasureTime frame
Lesser scores in Wong Baker Faces Pain Rating Scale (WBFRS) and Face, Legs, Activity, Cry, Consolability (FLACC) scale and Lesser variation from baseline values of physiological parameters (Hear rate and Heart rate variability depended stress levels) while administering 4% Articaine over 2% lidocaineTimepoint: 1 week—

Secondary

MeasureTime frame
Lesser scores in Wong Baker Faces Pain Rating Scale (WBFRS) and Face, Legs, Activity, Cry, Consolability (FLACC) scale and Lesser variation from baseline values of physiological parameters (Hear rate and Heart rate variability depended stress levels) while Local anaesthetic administration using Buccal infiltration technique over Inferior Alveolar Nerve BlockTimepoint: 1 week—

Countries

India

Contacts

Public ContactDr J Nagarathna

Government Dental College and Research Institute, Bangalore

nagarathnagiri_1975@yahoo.co.in9449631391

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026