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Comparison between the effects of intravenous clonidine and dexmedetomidine on shivering after spinal anaesthesia

A prospective randomised double-blind comparative study between intravenous clonidine And dexmedetomidine for post-spinal anaesthesia shivering

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/09/027985
Enrollment
54
Registered
2020-09-23
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 8- Other Procedures

Interventions

Intervention1: Effects of intravenous dexmedetomidine on shivering after spinal anaesthesia: One group of 27 patients will receive intravenous dexmedetomidine 0.5mcg/kg after onset of post spinal shi

Sponsors

Midnapore Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age- 18-60 years 2. ASA grade 1 & 2 3. OT temp between 24 to 32 degree 4. Gynaecology and obstetrics, surgery, and orthopaedic operations

Exclusion criteria

Exclusion criteria: 1. Preexisting cardiac diseases 2. Pulmonary diseases 3. Bleeding or coagulation disorders 4. Renal or hepatic disease 5. Neuromuscular disorder 6. Psychiatric disorder 7. Hyperthyroidism 8. Deformity of the spinal column 9. Urinary tract infection 10.Severe diabetes or autonomic neuropathies 11.Known history of substance or alcohol abuse 12 Patient receiving any premedication 13.Cutaneous infection 14.Contraindication of spinal anaesthesia 15.Conversion to GA at any time intraoperatively 16.Patient refusal

Design outcomes

Primary

MeasureTime frame
We will compare the effects of clonidine and dexmedetomidine on shivering in terms of time of cessation of shivering, response rate and recurrence rate of shivering following spinal anaesthesia Timepoint: At baseline and at intervals of every 5 min for first 30 min and every 15 min for rest of the observation period after starting point of shivering.

Secondary

MeasureTime frame
We will observe the change in blood pressure, heart rate, respiratory depression, nausea vomiting, dry mouth, effect of sedation in patients who will receive clonidine and dexmedetomidine separately.Timepoint: At baseline and at intervals of every 5 min for first 30 min and every 15 min for rest of the observation period after starting point of shivering.

Countries

India

Contacts

Public ContactSuman Chattopadhyay

Midnapore Medical College and Hospital

sumanc24@gmail.com7044072472

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026