Skip to content

To compare sedative and analgesic effect of intravenous Ketamine-Propofol combination versus intravenous Ketamine-Dexmeditomidine combination in patient under going upper limb surgeries under regional anaesthesia

Comparision of Ketamine-Propofol versus Ketamine-Dexmeditomidine in sedation and analgesia in patient under going upper limb surgeries under supraclavicular block.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/09/027976
Enrollment
70
Registered
2020-09-23
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: S599- Unspecified injury of elbow and forearm

Interventions

Intervention1: Sedation score comparison: Drug combination will be given to the patient through the intravenous route for sedation in patients under going upper limb surgery in supraclavicular block

Sponsors

Shree Krishna Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patients ASA 1-3 physical status 2)Age 18-70 yrs of either sex 3)Patient posted for elective and emergency upper limb surgeries (in emergency surgeries NBM for 6 hour is needed , those patients are not NBM for 6 hour for solid are not included in study) 4)Patient with body mass index (BMI) 18-40 kg/m2

Exclusion criteria

Exclusion criteria: 1)Hypersensitivity to local anesthetic agents 2)Altered mental status (phychiatric and anxiety disorder) 3)History of allergy to study drugs 4)Patient on sedative and hypnotic medications 5)Patient with chronic pain or on painkiller 6)Patient with severe hepatic or kidney impairment 7)Patient having history of thyrotoxicosis, uncontrolled hypertension, cardiac,chest or neurological diseases 8)Pregnant or breast feeding female

Design outcomes

Primary

MeasureTime frame
RAMSAY SEDATION SCALE Quality of Sedation will be measured according to below mentioned score of RAMSAY SEDATION SCALE 1) Anxious and agitated or restless ot both 2) cooperative , oriented and tranquil 3)Responds to command only 4)Brisk response to light glabellar tap 5) Sluggish response to light glabellar tap or loud auditory stimulus 6)No response to light glabellar tap or loud auditory stimulusTimepoint: intraoperatively at 5,10,15,20 min......

Secondary

MeasureTime frame
Heart rate,Respiratory rate,Blood pressure,spo2Timepoint: intraoperatively at 5,10,15,20min......

Countries

India

Contacts

Public ContactMadhavi Chaudhari

Pramukh Swami Medical College

mehuldm@charutarhealth.org8140732971

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026