None listed
Conditions
Interventions
Intervention1: Standard Preventive Regimen plus Ayurveda Rasayana (Chyawanprash): Standard Preventive Regimen for healthcare workers(Standard precaution, Hand hygiene, Personal protective equipment ,
Sponsors
Central Council for Research in Ayurvedic Sciences CCRAS
Eligibility
Inclusion criteria
Inclusion criteria: All healthcare professionals and staff of age group between 25 to 60 years willing to participate, negative for SARS- Cov-2 at screening,(tested by rt-PCR), at KGMU , without co-morbid condition with exposure/chance of exposure to COVID 19 positive cases. Who are willing to provide signed informed consent. High Risk Group- It includes doctors, nursing staff and other paramedical staff like attendant who are directly looking after and examining COVID patients. Low risk- other faculty members who are present in the institute but not visiting corona ward.
Exclusion criteria
Exclusion criteria: Pregnant and lactating females. Immune compromised and co morbid condition cases. Laboratory confirmed COVID-19 with or without symptoms Known allergy to any of the medications used in this trial. Not willing to participate in the study. Subjects who are taking any other medicine as prophylaxis such as HCQ.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage of participants with SARS- Cov-2 positivity as estimated by RT-PCR of nasopharyngeal swab / Chemiluminiscence assay after 1 month of consuming Chyawanprash.Timepoint: Baseline, 7th day,15th day,and 30th day | — |
Secondary
| Measure | Time frame |
|---|---|
| Safety profile of the intervention as estimated by LFT, KFT and other haematological & biochemical investigations. Presence or absence of AE/ADR. Number of participants who developed any infective diseases during the trial period (bacterial /viral/ fungal / etc.) and percentage of participants with Upper respiratory tract illness during the period. Immune and inflammatory markers (IgG, IgM, IgE, Hs-CRP TNF - α,IL6, IL10) baseline and end of treatment. Timepoint: Baseline ,on 7th day,on 15th day,and completion of study 30th day. | — |
Countries
India
Contacts
Public ContactDr Satyendra Kumar Sonkar
KGMU ,Lucknow
Outcome results
None listed