Health Condition 1: K742- Hepatic fibrosis with hepatic sclerosis
Conditions
Interventions
Intervention1: Nil: Nil
Intervention2: Nil: Nil
Control Intervention1: Retrospective study: This is a retrospective single-center study performed at ILBS, New Delhi. All pediatric acute liver failure
Sponsors
Dr Akansha Sangwan
Dr Gaurav Sindwani
Eligibility
Inclusion criteria
Inclusion criteria: All pediatric ALF patient ( < 18 years) who underwent LDLT between March 2010 â?? March 2020 in Institute of Liver and Biliary Sciences, New Delhi.
Exclusion criteria
Exclusion criteria: Chronic liver disease and patients with acute on chronic liver failure will be excluded. Patients whose complete data is not available will also be excluded from our study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the difference in intraoperative ionotropes requirement in between the plasmapheresis and non plasmapheresis groups.Timepoint: 48 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the total intraoperative amount of crystalloids and colloids administered in plasmapheresis and non plasmapheresis group Timepoint: 48 hours;To compare the total intraoperative blood products administered in plasmapheresis and non plasmapheresis group Timepoint: 48 hours;To compare ICU and total hospital stay in two groupsTimepoint: 60 days;To compare the amount of phenylephrine and adrenaline administered during reperfusion of the liver to maintain hemodynamics in between the two groupsTimepoint: 48 hours;To compare the difference in time of extubation in two groupsTimepoint: seven postoperative days;To compare the intraoperative ABG changes in between the two groups (after induction, dissection phase, anhepatic phase, post reperfusion and after shifting)Timepoint: 48 hours | — |
Countries
India
Contacts
Public ContactDr Gaurav Sindwani
Institute of Liver and Biliary Sciences
Outcome results
None listed