Health Condition 1: N18- Chronic kidney disease (CKD) Health Condition 2: A150- Tuberculosis of lung
Conditions
Interventions
None listed
Sponsors
Indian Council of Medical Research Technically Approved Awaiting for further response
Eligibility
Inclusion criteria
Inclusion criteria: 1- Tuberculosis (TB) with Chronic Kidney Disease (CKD) group a. Age group between 18 to 70 b. Patients with CKD having tuberculosis and received treatment minimum for two weeks. 2- Tuberculosis (TB) without Chronic Kidney Disease (CKD) group a.Age group between 18 to 70 b.Patients with tuberculosis received treatment minimum for two weeks. 3-Chronic kidney Disease patients with dialysis group a.Age group between 18 to 70 b.Patients of CKD on maintenance of dialysis and having tuberculosis received treatment minimum for two weeks.
Exclusion criteria
Exclusion criteria: a.Human immunodeficiency virus (HIV) infected subjects b.Viral Hepatitis c.Any Hepatic Disease Subjects d.Renal transplantation subjects b.Acute Kidney Injury Subjects c.Non-adherence to medication: It is defined as If patients take less than 80% of their prescribed medication(s), they are considered nonadherent. d.Pregnant women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary Outcomes:- a)ATT related Side effects b)Population Pharmacokinetic model analysis of ATT drug Timepoint: 3 Years | — |
Secondary
| Measure | Time frame |
|---|---|
| a) Identification of various attributable factors responsible for alteration of the drug level. Timepoint: 3 years | — |
Countries
India
Contacts
Public ContactDr Ravindra Prabhu A
Kasturba Medical College Manipal,Manipal Academy of Higher Education, Manipal
Outcome results
None listed