Health Condition 1: K135- Oral submucous fibrosis
Conditions
Interventions
Intervention1: Group I - combination of Injection Pentoxyfylline and injection Dexamethasone: 1mg/ml Pentoxyfylline biweekly,3months.
4mg/ml dexamethasone biweekly for 3 months.
Control Intervention1
Sponsors
sharad pawar dental college wardha maharashtra
Eligibility
Inclusion criteria
Inclusion criteria: 1) Patients clinically diagnosed as having Grade II, III IV OSMF. 2) No obvious malignant disease in surroundings
Exclusion criteria
Exclusion criteria: 1) Patient allergic or hypersensitive to the prescribed drugs. Patients who have previously exhibited intolerance to PTX or other xanthines such as caffeine, theophylline, etc. 2)Patient who have been treated with Intralesional injections/surgical modality. 3) Systemically compromised patients. 4) Pregnant or lactating mothers. 5) Patients with trismus of oral cavity due to reasons other than OSMF like TMJ ankylosis, Temporomandibular disorders, Myositis Ossificans etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mouth openingTimepoint: every 1 month for 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| reduction in burning sensationTimepoint: every 1 month for 6 months;quality of lifeTimepoint: every 1 month for 6 months;Functional improvementTimepoint: every 1 month for 6 months;Down staging of grading of Oral Submuacous fibrosisTimepoint: every 1 month for 6 months | — |
Countries
India
Contacts
Public ContactSEEMA DENGRA
DATTA MEGHE INSTITUTE OF MEDISCAL SCIENCES. DEEMED TO BE UNIVERSITY.
Outcome results
None listed