Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Reversal from muscle relaxants with neostigmine without TOF monitoring.: The first researcher will count the time since last vecuronium administration and assess the subjects spontaneou
Sponsors
P Namrata Reddy
Eligibility
Inclusion criteria
Inclusion criteria: Patients undergoing elective surgeries requiring general anaesthesia with endotracheal intubation. ASA grade 1 and 2 patients Patients aged 18-60 years Patients having modified Mallampatti grade 1 and 2 score Â
Exclusion criteria
Exclusion criteria: Patientâ??s refusal Emergency surgeries ASA grade 3 and 4 patients Patients with age less than 18 years and more than 60 years Elective surgery Awake extubation or postsurgery intensive care admission Body mass index >35 kg/m2 Hepatic disease, hypoalbuminemia, renal insufficiency, neuromuscular disease Consumption of drugs known to affect neuromuscular transmission; Contraindications to vecuronium/ neostigmine and/or glycopyrrolate A history of hypersensitivity or allergic to anaesthetic agent given Difficulty accessing the TOF measuring device in the ulnar nerve. Factors causing delayed awakening such as electrolyte imbalance, hyperglycemia, hypoglycemia, hypercapnia, hypothyroidism, etc
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare if neostigmine reversal without Train of Four monitoring was equivalent to reversal using Train of Four monitoring with respect to the following parameters: SpO2 Respiration patterns Airway problemsTimepoint: After extubation and every 10minutes thereafter for 30minutes(T1, T2, T3) | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare incidence of residual paralysis in both groups.Timepoint: After extubation and every 10minutes thereafter for 30minutes(T1,T2,T3) | — |
Countries
India
Contacts
Public ContactDr S K Wahane
Guide (JLNHRC, Bhilai)
Outcome results
None listed