Skip to content

Role of vasopressin during hysteroscopic surgery for fibroid.

Intra lesional Vasopressin administration during Hysteroscopic Myomectomy: A randomized clinical trial.

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/09/027811
Enrollment
126
Registered
2020-09-15
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N858- Other specified noninflammatory disorders of uterus

Interventions

Intervention1: Intra lesional vasopressin injection: Before resectoscopic myomectomy, diagnostic hysterocopy will be done and diluted vasopressin will be injected into the sub mucous fibroid using a c

Sponsors

Dr SMurali
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with Type0 ,1 and 2 myoma (Submucous myoma) who are scheduled to undergo hysteroscopic myomectomy

Exclusion criteria

Exclusion criteria: 1. Myoma > 5cm size 2. Acute PID 3. Use of preoperative GnRH agonists 4. Endometrial premalignant or malignant pathologies 5. Women with cardiopulmonary diseases, bleeding diathesis and renal disease. 6. Patients with multiple submucous myoma. 7. Hypertension.

Design outcomes

Primary

MeasureTime frame
To compare the operative time between patients in whom intralesional vasopressin has been administered and patients in whom it was not administered during hysteroscopic myomectomy.Timepoint: Beginning of surgery to end of surgery. Time point is immediately after surgery.

Secondary

MeasureTime frame
To compare blood loss, fluid overload, visual clarity and complications in between patients in whom intralesional vasopressin has been administered and patients in whom it was not administered during hysteroscopic myomectomy.Timepoint: From beginning of surgery till end of surgery and at 2 weeks (for complications)

Countries

India

Contacts

Public ContactDr S Murali

JIPMER, Pondicherry

muralidraiims@gmail.com08940760837

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026