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comparison between efficacy of different local anesthetics

A Comparative Evaluation of Efficacy of Inferior Alveolar Nerve Block with Conventional, Pre-heated and Buffered 2% Lignocaine in Patients with Symptomatic Irreversible Pulpitis- A Randomized Clinical Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/09/027796
Enrollment
180
Registered
2020-09-14
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis

Interventions

Intervention1: Anesthetic agent: Group C: Conventional local anesthesia Intervention2: Anesthetic agent: Group A: 1.8 ml of Preheated lidocaine with 1:80000 epinephrine , by inferior alveolar nerv
to ensure that sodium bicarbonate is dissolved completely. ïâ??§ The Cartridge will be loaded into metal syringe and then injected. Control Intervention1: Anesthetic agent: Group C: 1.8 ml of lidoc

Sponsors

Dr Namita Gandhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Both male and female patients between 18-60 years of age will be included in the study. 2. Patients diagnosed with symptomatic irreversible pulpitis with or without apical periodontitis. 34 3. Patient should have actively experienced moderate to severe pain pre operatively on VAS scale.32 4. A written informed consent will be taken from all the patients and only those patients ready to sign the consent form will be included in the study. 5. Patients diagnosed with symptomatic irreversible pulpitis in mandibular molar teeth will be included in study.

Exclusion criteria

Exclusion criteria: Patients allergic to local anesthetics or known allergy to sodium bicarbonates will be excluded from study. 2. Pregnant and lactating patients will be excluded from study. 3. Patients taking any analgesics, antibiotics, sedatives, and antianxiety drugs on regular basis or before 24 hrs. of treatment will be excluded. 4. Patient having history of significant medical condition will be excluded from study. 5. Patient having necrosed tooth with sinus tracts/local gum swelling around the affected tooth. 6. Patients with severe periodontitis and poor oral hygiene.

Design outcomes

Primary

MeasureTime frame
1.To evaluate the efficacy of preheated local anaesthetic ie. 2% Lignocaine in patient with symptomatic irreversible pulpitis on giving inferior alveolar nerve block checked on VAS scale. 2.To evaluate efficacy of buffered local anaesthetic ie.2% Lignocaine on VAS scale.3.To evaluate efficacy of conventional local anaesthetic ie. 2% Lignocaine checked on VAS scale.4.To compare the efficacy of conventional, pre-heated and buffered local anesthetics ie. 2% Lignocaine checked on VAS scale.Timepoint: pre and post operatively

Secondary

MeasureTime frame
To compare pain on injection between conventional, pre-heated and buffered local anaesthetic ie. 2% Lignocaine in patients with symptomatic irreversible pulpitis on Administrating inferior alveolar nerve block checked on VAS scale on mandibular posterior teeth.Timepoint: after inferior alveolar nerve block

Countries

India

Contacts

Public ContactDr Namita Gandhi

HOD,and Professor of conservative dentistry and endodontics. KM shah dental college

nshah7873@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 11, 2026