Health Condition 1: K70-K77- Diseases of liver
Conditions
Interventions
Intervention1: Patient controlled intravenous fentanyl administration post living donor liver transplant: PCA settings
Demand bolus of 15mcg, lock out interval of 15 minutes,maximum four boluses allow
Sponsors
PRIYANKA CHUTTANI
Eligibility
Inclusion criteria
Inclusion criteria: Adult chronic liver disease patients undergoing live donor liver transplant who will be extubated on postop day 1
Exclusion criteria
Exclusion criteria: Paediatric patients less than 18 years of age Alcohol abstinence of less than 4 weeks History of drug abuse Mentally retarded Acute liver failure patients Presence of hepatic encephalopathy at the time of transplant
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Post operative fentanyl consumption in the first 24 hoursTimepoint: Post operative fentanyl consumption in the first 24 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| Fentanyl consumption, VAS, sedation score, post op respiratory function (no. of ball rise on incentive spirometry),timing of ambulation, duration of ICU stay and respiratory complications - need for re intubation, evidence of respiratory depression, episodes of nausea, vomiting, surgery related complication including graft dysfunction, non-function and portal vein thrombosisTimepoint: cumulative fentanyl consumption during first 72 hours following transplant,VAS at rest, during coughing, position change and sedation score post op at 24,48 and 72 hours, post op respiratory function at 24,48 and 72 hours, episodes of nausea, vomiting and respiratory depression during first 72 hours following transplant | — |
Countries
India
Contacts
Public ContactDr Gaurav Sindwani
Institute of Liver and Biliary sciences
Outcome results
None listed