Health Condition 1: C858- Other specified types of non-Hodgkin lymphoma
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patient must have histologically and cytologically confirmed lymphoma; patient receiving chemotherapy for the treatment of lymphoma; capable of giving informed consent; willing to participate in the study.
Exclusion criteria
Exclusion criteria: Patient below 18 years of age, history of cognitive impairment and Alzheimerââ?¬•s disease; history of depression; history of head injury; patient with history of any type of cancer; any cancer patient with brain involvement; ongoing psychotropic medications; history of schizophrenia or any other neuropsychiatric disorders; habit of any substance of abuse; using any concurrent medication for any neuropsychiatric disorder; using anti-inflammatory drugs; incompetent for interview; not willing to participate and give consent for the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Possible correlation of different inflammatory mediators with chemotherapy-related cognitive impairment Timepoint: a)Before 1st cycle of chemotherapy (at baseline) b)Before 4th cycle of chemotherapy (T2) c)After 6th cycle of chemotherapy (T3) | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in the quality of life of lymphoma patients after receiving chemotherapyTimepoint: At the end of 6th cycle of chemotherapy;Dysregulation of serum levels of peripheral inflammatory markers after cycles of chemotherapyTimepoint: After six cycles of chemotherapy;Probable occurrence of cognitive impairment after receiving consecutive cycles of chemotherapyTimepoint: AFter 6 cycles of chemotherapy;Probable occurrence of depression after receiving consecutive cycles of chemotherapyTimepoint: After 6 cycles of chemotherapy | — |
Countries
India
Contacts
Rajiv Gandhi Cancer Institute and Research Centre