Health Condition 1: K669- Disorder of peritoneum, unspecified
Conditions
Interventions
None listed
Sponsors
Zydus hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1. All patients undergoing cytoreductive surgery for peritoneal metastases from colorectal, ovarian, gastric and appendiceal primary tumors and peritoneal mesothelioma will be included. 2. Only patients with biopsy proven PM will be included (pathological evaluation is not mandatory prior to CRS if imaging or exploration confirms the presence of disease). 3. Patient undergoing debulking procedures will be included 4. For ovarian cancer, only patients with FIGO stage III-C or IV-A will be included. Patients undergoing surgery at first diagnosis, after NACT and those undergoing surgery for recurrent disease will be included. Patients without peritoneal disease will be excluded.
Exclusion criteria
Exclusion criteria: • Patients undergoing second look procedures with no evidence of peritoneal metastases will be excluded. • Patients undergoing palliative procedures that do not involve tumor debulking will be excluded unless the goal of surgery was to obtain a complete cytoreduction i.e. procedures performed with the intention of palliation alone like a diverting oâ??stomy will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Disease distribution in the peritoneal cavityTimepoint: At 6 months, after completion of recruitment and at 1 year, 3 years and 5 years from the end of recruitment | — |
Secondary
| Measure | Time frame |
|---|---|
| Morphology of peritoneal metastasesTimepoint: At the time of surgery;Overall survivalTimepoint: At 1 year, 3 and 5 years after recruitment;Pathological response to systemic chemotherapyTimepoint: At the time of surgery;Pattern of lymph node involvementTimepoint: At the time of surgery;Progression-free survivalTimepoint: At 1, 3 and 5 years after recruitment | — |
Countries
Algeria, Andorra, Angola, Antigua and Barbuda, Argentina, Armenia, Australia, Austria, Azerbaijan, Bahamas, Bahrain, Bangladesh, Barbados, Belarus, Belgium, Belize, Benin, Bhutan, Bolivia, Bosnia and Herzegovina, Botswana, Brazil, Brunei Darussalam, Bulgaria, Burkina Faso, Burundi, Cambodia, Cameroon, Canada, Cape Verde, Central African Republic, Chad, Chile, China, Colombia, Comoros, Congo, Cook Islands, Costa Rica, Cote d'Ivoire, Croatia, Cuba, Cyprus, Czech Republic, Democratic People's Republic of Korea, Democratic Republic of the Congo, Denmark, Djibouti, Dominica, Dominican Republic, Ecuador, Egypt, El Salvador, Equatorial Guinea, Eritrea, Estonia, Ethiopia, Fiji, Finland, France, Gabon, Gambia, Georgia, Germany, Ghana, Greece, Grenada, Guatemala, Guinea, Guinea-Bissau, Guyana, Haiti, Honduras, Hong Kong, Hungary, Iceland, India, Indonesia, Iran (Islamic Republic of), Iraq, Ireland, Israel, Italy, Jamaica, Japan, Jordan, Kazakhstan, Kenya, Kiribati, Kuwait, Kyrgyzstan, Lao People's Democratic Republic, Latvia, Lebanon, Lesotho, Liberia, Libyan Arab Jamahiriya, Lithuania, Luxembourg, Macedonia, Madagascar, Malawi, Malaysia, Maldives, Mali, Malta, Marshall Islands, Mauritania, Mauritius, Mexico, Micronesia (Federated States of), Monaco, Mongolia, Montenegro, Morocco, Mozambique, Myanmar, Namibia, Nauru, Nepal, Netherlands, New Zealand, Nicaragua, Niger, Nigeria, Niue, Norway, Oman, Other, Pakistan, Palau, Panama, Papua New Guinea, Paraguay, Peru, Philippines, Poland, Portugal, Qatar, Republic of Korea, Republic of Moldova, Romania, Russian Federation, Rwanda, Saint Kitts and Nevis, Saint Lucia, Saint Vincent and the Grenadines, Samoa, San Marino, Sao Tome and Principe, Saudi Arabia
Contacts
Public ContactAditi BHATT
Zydus hospital, surgical oncology, room no 5
Outcome results
None listed